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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central pnis enlargement tip vimax male virility sexual enhancement enlargment free penile pills sample natural penis elargement technique pnis enlargement result free penis elargement technique best penis enhancement surgery pennis enlargement surgeries

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You can do a Google search for “Viagra jokes” and turn up over 30,000 webpages. But as most men (and women) know, erectile dysfunction (sometimes called ED or impotence) is no joke. Every guy has had a time where he cannot have or sustain an erection. The flu, exhaustion, a long bout of sex with no breaks, even other worries (work, finances, even sexual performance anxieties) can affect erectile abilities. For some men, though, ED can become a recurring problem. Diabetes, high blood pressure, or clogged arteries can reduce blood flow to the penis. ED can also be caused by physical blockages (like prostate enlargement), hormonal imbalance, or medications (like antidepressants). For about 20% of men with ED, psychological issues may be contributing to the problem. It’s important to realize that many of these causes have nothing to do with age! If you are experiencing problems with ED, it doesn’t mean you’re getting “old” – think of it as your body signaling for a change! Fitting Viagra Into the Picture For many of the causes of ED, managing the underlying illness or problem will be enough to improve sexual function. In some cases, however, Viagra can help with sexual activity. Viagra works on some of the muscles in your penis that help control the blood flow (when we’re teens, the control over these muscles isn’t always perfect which is why erections would sometimes pop up at inconvenient moments). Viagra encourages these muscles to let more blood flow into the penis when the time is right. The effect can last up to four hours, so taking Viagra the day that you would like to have sex will ensure that it can work effectively for you. Don’t worry that it will cause you to have an erection before you are ready for one – it works in conjunction with sexual stimulation. Viagra Does Not Increase Sex Drive While Viagra assists with developing with erections, it is not an aphrodisiac. In other words, it helps with the mechanics but not sex drive. If you don’t feel like having sex, the drug isn’t going to change your mind! Many men, however, do find that as they feel more confident about their ability to gain and maintain an erection they feel happier about being physically intimate. Viagra can also have side effects; many are mild (indigestion and flushing) but a few are serious, so make sure your doctor gives you a list of things to look out for! Mix and Match Safely Because Viagra is a very potent drug, your physician will ask you lots of questions before pulling out his prescription pad. Because Viagra affects your blood flow, if you have significant heart problems, history of stroke, or untreated diabetes or high blood pressure, Viagra may not be the best match for your other health needs. Many drugs that affect your heart and circulation can interact in very harmful ways with Viagra, so make sure to take a list of all the drugs you’re taking with you when you visit the doctor. Lastly, if you use recreational drugs, do yourself a favor and speak frankly with your doctor – he’ll keep it confidential – because some of these drugs (including “poppers” or amyl nitrate) can be a fatal mix with Viagra. Are you ready? If you’ve been experiencing ED you’re ready to take the next step –see your doctor to find out if Viagra is right for you! penis enlagement traction device vimax easy enlargement free penis surgery way penis enlarement traction device penis enargement traction device vimax natural penis enlargement and lengthening pnis enlargement supplement vimax safe penis enlargement penis elargement pills pennis enlargement stretcher

Rosacea, or acne rosacea, is clinically defined as a chronic "acneiform" disorder which affects both the skin and the eyes. It's location on the human body is usually the most sun-exposed areas, such as the face and the chest. Rosacea usually varies in severity, and manifests in epsiodes of flushing and inflammation of the affected areas. Clinical research has shown inflammatory episodes to be triggered and/or worsened by the consumption of spicy foods, alchoholic beverages, and hot drinks. The skin lesions which can accompany rosacea (acne rosacea), differ from acne in that spots of inflammation do not swell with fluid and come to a "head" like acne vulgaris postules do. Rosacea is most common in adults between the ages of 30 and 60, and women are affected almost twice as often as men according to some studies. Although there is much medical speculation that rosacea and acne rosacea frequently affect fair skinned people of European and Celtic descent, there have never been any conclusive findings supporting this theory. So, if you are an individual who suffers from rosacea, what are your treatment options, and what actions can you take to relieve these symptoms? One course of action is to have a dermatologist prescribe a common rosacea medication, such as oral tetracycline, and maybe a topical ointment as well, like erythromycin. If you want to skip the doctor's office route, there are now some excellent herbal and all natural rosacea treatments available today that will eliminate rosacea just as well as, if not better than, their prescription counterparts. Regardless of the course of treatment you end up choosing to cure your rosacea symptoms, there are some guidelines you can adhere to in your daily life and skin care regimen that will also help alleviate your rosacea symptoms. Since rosacea and acne rosacea symptoms are caused in part by the dilation or enlargement of tiny blood vessels under the skin's surface, avoiding hot and spicy foods, alcohol, and hot beverages should become a general rule of thumb in your daily life. Also, a diet rich in multiple vitamins and minerals, especially vitamin A, has show to benefit rosacea and acne rosacea sufferers. If you are a smoker, it is imperative you quit. Smoking can aggravate rosacea, and causes problems with circulation, which can lead to other skin problems. Wear a good, non-irritating (PABA free) sunscreen at all times, especially on your face and chest. Be sure to use a gentle skin cleanser without harsh abrasives or other harsh chemicals/ingredients. Excessive alcohol and harsh chemicals abound in many cleansers, so be sure your cleanser is free of irritants. There are some great anti-redness masks, serums, and gentle cleansers out there for rosacea sufferers that will soothe and calm the skin, bringing back it's normal color and balance. The good news is, Rosacea is a very treatable problem now, and there are some great natural products available to those who can't afford a dermatologist, or simply have an aversion to doctor's visits and man-made medications and prefer to "go natural". With these high-tech nutreceuticals, your skin will be back to it's calm, gorgeous self in no time! penis enlagement system penis enhancement secret com enlargement pnis pnis pump vimax homemade penis enlargement penis enhancement pump herbal natural penis enhancement pennis enlargement pills product pnis enlargement herb pennis enlargement stretcher

There has much been written about the G-Spot (named after its discoverer, Grafenburg). It is an area within the woman’s vagina that, when stimulated, can bring intense pleasure. Now due to the advances in non-invasive anatomical investigation with MRIs, CAT scanners, and other highly sensitive investigative instruments, the human form is revealing more of its secrets. Here we examine two newly discovered pleasure areas within the general area of the female genital zone. The U-Spot. The U-spot is a small area of highly sensitive erectile tissue located just above and on both sides of the urethral opening. Some American clinical researchers have recently discovered this aera, and proved that if it was stimulated by caress, with the tongue, the head of the penis, or even a lubricated finger, it brought an unexpected and highly intense erotic response. This is not the urithiral opening, but just above and to ether side of it. There is no U-spot underneath the urithra towards the vagina. Care should be taken when attempting to stimulate it, and ask for feedback from your partner. The Anterior Fornix Erogenous Zone (also known as the A-Spot or T-Spot ,or just AFE) Recently a Malaysian physician reported the existence of a highly sensitive erotic area just above the cervix, at the innermost point of the vagina. The cervix is a part of the uterus that extends slightly into the vagina. As it so extends, it leaves a depressed circular area, technically called the anterior fornix. Tests have shown that pressure on this area causes the vagina to lubricate very quickly. In fact, direct stimulation of the AFE zone can cause immediate and profound contractions only found in orgasm. Some anatomists say the AFE zone is really a evolutionary degenerated prostate, homologous to a man’s prostate gland that would be located in just about the same place. The AFE – Zone and Erotic Pleasure Technically, the AFE Zone is a vortex of the nerves that carry information from your whole genital to the spinal cord and brain. These nerves, when stimulated, send arousal signals to the part of your nervous system which enhances engorgement of appropriate areas, ans is responsible then for sexual arousal. This is also true for women that normally are not sexually responsive. Obviously the most easy way to locate the AFE zone is to slide the fingers halfway up the posterior vaginal wall you will find a larger area than the G-spot, which is slightly rougher than the normal vaginal wall. Recently specially shaped vibrators (long, then and with the neck bent in an oblique way) have come onto the marketplace which are meant for self-stimulation of the AFE zone. Size Matters? This is long-standing debate on the benefits or deficiencies of a large and long penis. In the case of the AFE zone, no matter the size of a man’s penis, he must be experienced to find, and then stimulate the AFE zone. For the man with a shorter penis, there are some advantagous positions to shorten the woman’s uterous, and thus still find a way to stimulate the AFE zone as well. The use of the advanced missionary, where the woman will have her legs drawn to her breast, with the man’s arms both holding her legs apart, and suspending himself, will create, even if he is short and small of penile stature, complete penetration and stimulation of the AFE zone. Due to small depression at its location, and roughness of the area, it also provides some intense pleasure for the man as well. penis enlargment drug penile enlargment secret penis enlagement surgery cost free pennis enlargement pills penis enlagement pill pro solution guide to pennis enlargement best penile enlargement pills penile enlargement tool pennis enlargement stretcher

What are penis enlargement exercises? Penis enlargement exercise is the term used to describe the methods of enlarging penis through the use of exercises. It has been a proven method that has been used for centuries by men to enlarge their penis safely, effectively and permanently without resorting to invasive and expensive penis surgery, pumps, hanging weight and other dangerous methods. Due to its numerous benefits, it has become a popular enlarging methods used by thousand of men worldwide to achieve their desire penis size. What is the optimum time of day to do penis exercise? There is no specific time frame in which you have to exercise your penis. Most men do their penis exercises first thing in the morning after they wake up while others do it before they went to bed at night. The time of day you exercise your penis will not affect your progress in any way. How does penis enlargement exercises work to enlarge penis? In your penis, there are three main structures: 1 small chamber called Corpora Cavernosa which surrounds the Urethra and 2 long cylinders called Corpora Cavernosa and it is the main blood holding chamber of the penis. These 3 chambers are made of erectile tissue which when sexually aroused, engorge with blood and become bigger. Your current penis size is limited in both width and length, by the maximum amount of blood Corpora Cavernosa can hold. The Corpora Cavernosa cannot become bigger itself but it can be gradually developed, strengthened and enlarged to hold far greater volumes of blood using penis exercises. Through the use of dedicated exercises, penile enlargement in both length and girth is achieved by forcing increased blood flow into the erectile tissue, thus stimulating the cells within them. The stressed cells will eventually repair, strengthen and thus a bigger, stronger and longer penis resulted. Can I do the penis exercise more than once daily? No, you are encourage to give your penis a break as the penile tissue require approximately one day to rebuild. Exercising more than once daily will not allow your cells sufficient time to regenerate and cause you to experience lesser gains. Don't overdo it. How safe is penis enlargement exercise? If you use a methodical, well-structured and research penis exercise program, natural penis enlargement is completely safe. It is vital that you neither under nor over exercise your penis since too little exercise may result in limited penis gain, while over exercising or poorly applied techniques can leads to injury. With the emergence of free sites offering deliberately false, unsafe and potentially harmful information, it is crucial you only apply techniques that are tried, tested and come from reliable sources. After I have achieved my desired penis size and stop exercising, will the final outcome be permanent or temporarily? Penis enlargement by penis exercise techniques will results in permanent gains in both penile thickness and length. Final penis gain will not shrink in size once enlarged. That was why it was very popular among thousands of men worldwide.